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Vitamin C may encourage blood cancer stem cells to die

Vitamin C may tell faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers....


Toxic formaldehyde is produced inside our own cells, scientists discover

New research has revealed that some of the toxin formaldehyde in our bodies does not come from our environment -- it is a by-product of an essential reaction inside our own cells. This could provide new targets for developing cancer therapies....


Antiulcer drugs do not increase risk of Alzheimer’s disease

The use of proton pump inhibitors does not increase the risk of Alzheimer’s disease, according to a recent study. Proton pump inhibitors are a type of antiulcer drug that is commonly used among older people....


Explaining failure of retinoic acid trials against breast cancer: Timing key

Estrogen-positive breast cancers are often treated with anti-estrogen therapies. But about half of these cancers contain a subpopulation of cells marked by the protein cytokeratin 5 (CK5), which resists treatment -- and breast cancers with higher CK5 expression have poorer prognosis. These cells, which have characteristics of stem cells, often survive treatment to drive or even restart cancer growth. Previous work has shown that retinoic acid, a chemical that results from the bodys natural break...


On the path to vitamin A in rice

Biochemists have elucidated the structure of an enzyme that supplies carotenoid, investigators report. The lack of vitamin A in food is a major cause of health problems worldwide and can lead to blindness and even death. This is especially a problem in threshold or third-world countries, where children are likely to suffer from a lack of vitamin A or its precursor beta-carotene due to malnourishment....


Could calcium hold the key to fighting a dangerous hospital infection?

It lurks in hospitals and nursing homes, preying upon patients already weak from disease or advanced age. It kills nearly 30,000 Americans a year, and sickens half a million more. But new research shows that Clostridium difficile bacteria cant do all this without enough of a humble nutrient: calcium. And that new knowledge may lead to better treatment for the most vulnerable patients....