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Scientists find molecular link between Vitamin A derivative and mouse intestinal health

New research shows that all-trans-retinoic acid (atRA), the active form of vitamin A, regulates immune system responses in the mouse intestine by controlling expression of the protein HIC1 in cells known as innate lymphoid cells. These findings could suggest new ways to fight disease....

New symmetry-breaking method opens way for bioactive compounds

Chemists have developed a new catalytic method for symmetry breaking. The method can help synthesize important building blocks for bioactive compounds such as anticancer drugs....

Pregnant women deficient in vitamin D may give birth to obese children

Vitamin D deficiency in pregnant women could preprogram babies to grow into obese children and adults, according to a new study. Researchers found that 6-year-olds born to mothers with very low vitamin D levels during their first trimester had bigger waists -- about half an inch plumper on average -- than peers whose mothers had enough vitamin D in early pregnancy. These kids also had 2 percent more body fat....

How old antibiotic compounds could become tomorrow's life-saving drugs

As the fight against drug-resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics....

Vitamin A in cattle fodder is potentially protecting against cow's milk allergy

Infants can develop an allergy to cows milk that usually subsides by adulthood but may increase risk for developing other allergic diseases. The allergic reaction can, however, be prevented by two components of cows milk interacting together, as researchers now describe. Loading of vitamin A metabolite retinoic acid to the important milk protein beta-lactoglobulin in cows milk can prevent allergic reaction against the protein....

Upper limit for intake of folate is invalid: Government urged to fortify flour with folic acid

There is no need for an upper limit of folate intake, according to a study by Queen Mary University of London and the School of Advanced Study, University of London....

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